Welcome to the ACTS Learning Library, the centralized location for all ACTS educational offerings, including partner webinars and past Translational Science recordings.
NOTE: ACTS members receive complimentary access to webinars and recordings. Guests can create an account to view and purchase ACTS education.
Past Translational Science Recordings
Translational Science 2021
A Novel Online Course in Translational Science Offered by NCATS: Course Design, Content, and Evaluation Results
Description: The NCATS Education Branch is creating new education opportunities aimed at advancing understanding of translational science principles. In this panel, we highlight use of the case study method as an approach for teaching these emerging concepts and detail our first online translational science course, piloted in 2020 and open to the scientific community. The course teaches key principles of translational science including novelty, process innovation and efficiency, acceleration of timelines, and boundary-crossing partnerships, and highlights how these principles have been operationalized in a real-world project. The specific case examined the development of a compound to treat advanced metastatic cancer that is now in phase 1 clinical trials. The course was evaluated through pre- and post-course student surveys (n=100) and analyses showed significant improvements in translational science knowledge and alignment towards team science attitudes in translational research. Additional course outcomes and future directions for translational science education will be discussed.
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Accelerating Large-Scale Research: Methods for Creative Brainstorming and Strategic Action Planning
Description: Interdisciplinary collaboration is widely considered essential to addressing complex scientific and societal problems. Funding agencies are increasingly seeking team-based approaches to tackling research questions, and the Michigan Institute for Clinical & Health Research at the University of Michigan responded by deploying an initiative that encourages and supports the development of large-scale grants (e.g. NIH U- and P-series mechanisms). Attend this session to learn how to leverage various aspects of design thinking and strategic action planning intended to drive teams through stages of ideation all the way to group consensus around opportunities to pursue, including realistic next steps. We will discuss our aim to foster new methods of team thinking and doing that allow collaborative networks to create a shared research vision; to commit reasonable time and resources to advancing the research and partnerships; and to ultimately develop compelling large-scale grant applications to fund their big ideas and synergistic efforts.
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ACTS Business Meeting
Description: The ACTS Business Meeting is an opportunity for members to hear from ACTS President, Christopher Lindsell, PhD, about the accomplishments of the organization over the last year despite COVID obstacles. As well as hear about areas of focus for the current year. We will recognize our Board of Directors and formally welcome our incoming president, Karen Martinez-Gonzalez, MD MSc. We encourage members to attend and come with questions.
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Amplifying the CTSA Impact: Workforce Development Strategies Beyond the Consortium
Description: Promoting effective research requires CTSA hubs to engage in novel workforce development initiatives that extend beyond the Consortium. Given the scope of the future workforce and the need to move health research from bench to bedside, no single hub can contribute to this mission in isolation. Recent efforts to ensure reliability and replicability of data show how important it is for institutions to form collaborations that promote access to training resources and best practices developed by CTSAs. Join representatives from the University of Michigan, the Mayo Clinic, and Tufts CTSI as they describe and discuss successful collaborations between institutions.
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Approaches to Data Discovery: Connecting Researchers through Data
Description: Across the CTSA consortium a number of approaches have been taken towards facilitating the formation of translational research teams. This panel focuses on data discovery as an approach towards connecting researchers through data, as well as empowering those researchers to share and locate data for re-use. NYU Langone Health, Weill Cornell Medicine, and Northwestern University have taken different approaches to improving data discovery at their institutions, and are members of the Data Discovery Collaboration (DDC), a cross-institutional, platform-agnostic collaboration with the aim of enhancing the discovery of data in order to maximize its value. The objective of this panel is to present the approaches, successes, and challenges of each institution, and to discuss how the DDC enhances each of these institutional efforts. The panelists will also discuss the structure of and requirements for joining the DDC, innovations that will be made possible by this collaboration, and thoughts on upcoming challenges.
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Collaborative Conversations: Tackling Urgent Clinical Research Workforce Development Issues for Learning Health Systems
Description: There is a critical need to grow and sustain a knowledgeable and experienced clinical research professional workforce to support the academic clinical research enterprise. In addition to expanding training and education, organizational issues should be considered for the development of best practices for recruiting, training, retaining, and sustaining the workforce, in addition to addressing gaps in the existing pipeline of future clinical research professionals. A collaboration between University of Florida, Ohio State University and University of Washington CTSA hubs developed an initiative organized as “Collaborative Conversations- the Critical Need for Professional Workforce Development at Academic Medical Centers†became, due to COVID-19 a series of Zoom “Un-Meeting†webinars to focus on key clinical research professional workforce issues impacting the success of academic medical centers. Join this session to see shared data from the initial pre-conference needs assessment, as well as summary outputs from the individual webinars and post-meeting evaluations.
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Community-Academic Partnerships to Train Community Health Workers and Promotoras in Research
Description: Regardless of whether they have formal roles on study teams or informal roles of supporting research in communities where they work, community health workers and promotoras (CHW/Ps) are vital in the implementation of rigorous research in communities. The importance of the role of CHW/Ps has increased during the COVID-19 pandemic where they help to foster trust in communities to support health and research efforts. This session will describe an NIH-funded project from three CTSA-funded institutions in which the goal is to develop, demonstrate and disseminate competency-based research training for CHW/Ps. A community-academic partnership model will be described as a main method of training using peer Champions as the trainers in communities. A planned, broadly accessible toolbox of resources including culturally- and linguistically-appropriate materials will be discussed. Community partners from the universities associated with this project will discuss how training can be applied in their specific settings and potential adaptations to training in the field. Lastly, the planned dissemination of the training and toolbox using a newly-established network of community advisory boards at universities around the nation will be highlighted.
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Competency-Based Assessment for Clinical & Translational Team Science Training
Description: Clinical and translational science competencies have been described and used as guidelines for designing training experiences, but they have not been well integrated into training assessment plans for predoctoral and postdoctoral research trainees. In the apprenticeship model we use for research training, when asked when doctoral students have developed sufficient skills to defend their dissertation, or when postdoctoral scholars are ready for independent research positions, mentors often say, 'I know it when I see it'. However well intentioned, this approach leaves much to be desired, as trainees and mentors cannot articulate the competencies needed to lead clinical and translational research. During this interactive workshop participants will be divided into groups for role plays involving the use of this competency-based assessment approach in a research training scenario. Participants will be assigned roles as mentee, mentor, or observer, and provided with role-specific instructions.
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CTSA Community Reviewer Training Program: Increasing Diverse Perspectives in Pilot Grant Reviews by Integrating Community Input
Description: Learn about the NIH-supported Community Reviewer Training Program from the University of Arkansas for Medical Sciences, University of Southern California, University of California, Irvine, Ohio State University, and Virginia Commonwealth University. Community members have been trained to review CTSA pilot grant applications (based on the UAMS training model) and have participated in actual pilot grant reviews and study section meetings.Attend to learn more about the immediate goal of this project: to implement and assess across multiple CTSA hubs a scalable mechanism, allowing diverse representatives of communities affected by a disease or condition to meaningfully participate in review of pilot grant research proposals. Our long term goal is to enhance the review process across the CTSA consortium and other funding agencies, by systematic integration of a multi-faceted community perspective.
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Developing Maturity Models for Translational Science Communities: Research Informatics and Learning Health Systems
Description: Academic Health Systems associated with the CTSA consortia face continuous internal and network-level change management requirements, particularly in the health IT and research informatics investments which support translational science, learning health care system activities, and responsive national initiatives. This panel will describe the use of tools for organizational improvement called maturity models, which assess and guide planning using a sequence of discrete levels of formality and optimization for a class of processes and capabilities in one or more business domains. Join this session as the panel discusses current efforts and potential applications of maturity model frameworks to monitor dynamic improvement processes at the heart of translational research and learning health systems.
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Dimension Reduction and Feature Selection Methods: Reducing the Complexity
Description: Methods for reducing dimensionality and identifying important variables among a large number of predictors have become increasingly important in the areas of omics, health, and behavioral and social science research. The evolution of these statistical methods has impacted how we analyze data and interpret findings. This session will provide an introduction to statistical and machine learning methods for dimension reduction, variable selection, and classification methods. Emphasis will be placed on the types of research questions that can be answered, advantages over traditional methods, and interpretation of results. Primary topics will include: principal components analysis, orthogonal partial least squares, discriminant analysis, lasso regression, and random forests. Presenters will illustrate these methodologies with real data applications.
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Diversity and Inclusion in Translational Science: Success Stories and Lessons Learned
Description: NIH depends upon a pool of highly talented scientists from diverse backgrounds as a way to ensure a robust scientific workforce in the biomedical, clinical, behavioral and social sciences. The Clinical and Translational Science Awards (CTSA) Program supports diversity and re-entry research supplement opportunities to promote diversity and inclusion in health-related research and re-entry into biomedical and behavioral research careers. The goal of these supplements is to build a diverse clinical and translational research workforce that is prepared to improve the quality, safety, efficiency, and speed of clinical and translational science research nationally. In this session, we will highlight outstanding diversity and re-entry research supplement awardees who have used this opportunity to advance their research careers and improve public health for all. Success stories and lessons learned will be shared for an interactive discussion with attendees.
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Diversity in the Ivory: Uncovering the Hidden Curriculum for Research in Clinical and Translational Science
Description: Everyone in Clinical and Translational Science (CTS) understands the urgent need for diversity through the entirety of our pipeline, from trainee to leadership. Diversity and inclusion in CTS is essential to drive health equity as we engage in research to overcome health disparities that have existed since time immemorial. Diversity alone is insufficient, however; we need true equity, inclusion, and belonging. Issues with Diversity in the Ivory demonstrate critical concerns that are experienced by those in the workforce who belong to under-resourced and under-represented groups within CTS. Our work demonstrates that some of the reason we struggle with equity, inclusion, and belonging, is diversity-related “hidden curriculum†for researchers. Hidden curriculum is the set of messages and values that institutions and leadership unintentionally convey, such as; how research is actually conducted, decision making processes for promotion, and who is offered opportunities in our CTS community. Our work suggests that in addition to the need for uncovering research related hidden curriculum that applies to everyone, there is additional diversity-related hidden curriculum that is essential for diverse trainees, junior faculty, and mid-career faculty and for their mentors. In this interactive session, we will highlight some of these topics and ask attendees for their input. Our speakers, Joyce (Joy) E. Balls-Berry, PhD, MPE, and Felicity T. Enders, PhD, MPH, are both Black women who are leaders in the CTS research community. Our moderator, Minerva Orellana, MS, is a Latina PhD student in CTS. We hope participants will bring their thoughts and ideas to help us move the field forward in this engaging and interactive session. Participants should have a device (smartphone, tablet, or computer) handy for polling and discussion during the session.
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Drivers of Progress in Translational Sciences
Description: There are very different reasons why progress happens in science. The apple dropped from the tree onto Newton for discovery of gravity and Newtonian mechanics. This session will explore the stories behind discoveries and leaps that are happening now and the personal stories behind some of the efforts.
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Engaging Clinical Trial Participants through Effective Conversations
Description: A well run informed consent process, whether done in person or online, can positively affect participant recruitment, retention, engagement, honesty, consistency, and accuracy. It can also ensure their complete and thorough understanding of the trial itself and their role in it. While efficiency in the consent process is always a concern in the short term, in the long run, it's always worth investing the time and energy with your participants to establish rapport in the true sense of the word: a close and harmonious relationship, in which the people concerned understand each other's feelings or ideas and communicate well. In this workshop, NarrativePros leads an energizing, enjoyable and--most importantly--applicable dive into their tried and true techniques for having productive conversations that establish the kind of engagement, trust, and commitment every researcher wants from their participants. Through lecture and interactive exercises, apply improvisation techniques, intentional listening skills, and perspective shifting approaches to show you how to end up with truly informed participants.
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Getting Started with the National COVID Cohort Collaborative (N3C): What would you do with a billion rows of EHR data?
Description: This session will introduce attendees to the National COVID Cohort Collaborative (N3C): a nationwide effort collecting electronic health record data into a unified, secure database for analysis of COVID-related health outcomes. Built around team-science, N3C brings together clinicians, informaticians, and translational researchers of all experience levels to address the novel SARS-CoV-2 pandemic. In this session, you will learn the basics of N3C's data collection, and have a chance to develop COVID-19 study questions of their own with feedback from N3C experts. Speakers will guide you through the N3C registration process, introduce them to N3C resources and connect them to existing teams with similar interests.
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Growing a Diverse Team through Training Opportunities and Community Partnerships to Increase Diversity in Research Participation
Description: This panel discussion will highlight the Indiana Clinical and Translational Sciences Institute (CTSI)'s established, evolving, and expanding initiatives to promote diversity and inclusion throughout the research continuum. Dive into how the Indiana CTSI develops a diverse workforce—from a pipeline model for early and continual growth of diversity and key focuses on retention among underrepresented faculty, to turning to community partners. Learn how these have translated to increased engagement of underrepresented groups in recruitment efforts, with continued attention to and respect of the community's voice and priorities.
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Inclusion of Older Adults in Translational Research: Facilitating a Societal Imperative
Description: Older adults are the majority consumers of the treatment strategies and products resulting from clinical and translational research, and often have the most to gain from research advances. Yet, until recently, they have been included infrequently, minimally, or not at all in research evaluating treatments targeting their health conditions. The Older Adult Working Group of the Lifespan Enterprise Committee (under the NIH CTSA program) has developed comprehensive yet succinct presentations to address the intricacies of including older adults in clinical and translational research. This workshop briefly reviews both benefits and challenges to inclusion of older adults. It will be devoted to discussing inclusion strategies so that older adults can be fully represented in clinical and translational research. Speakers will discuss ways to tailor recruitment, consent processes, research protocols and/or planned assessments to accommodate cognitive, physical and logistical issues for older adults as well as consequent complexities of data interpretation.
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Learning Healthcare: Empowering Embedded, Pragmatic RCTs
Description: In recent years, various healthcare entities have implemented more formalized structure to promote aspiration and evolution toward becoming exemplar Learning Healthcare Systems (LHS). With a focus on “Learning from what we do, and then doing what we learnâ€, an LHS strives to ingrain a cycle of continuous discovery and implementation within the context of routine care delivery and hospital operations. To this end, our institution specifically targets the identification, development, and support of embedded, pragmatic, randomized controlled trial opportunities with a unique research infrastructure installation. During this session, we will detail the LHS Platform. We will touch on how our program leverages a translational, transdisciplinary, team science approach with strengths in clinical trial design and conduct, biostatistics, regulatory affairs, project management, data science and informatics, and community engagement. This organization enables unparalleled collaboration between clinical research and clinical operations, yielding a productive study pipeline and broad portfolio active within diverse specialty areas. We will highlight our methods and provide concrete examples of the Platform's functionality.
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Making Dissemination & Implementation Research Ubiquitous in Translational Science
Description: Health sciences seek to turn research knowledge into practice and benefit; this session raises awareness of the potential of Dissemination and Implementation (D&I) Sciences for improving population health. D&I sciences evolved rapidly in the past decade and have experienced a recent surge. Developments are occurring in theories, frameworks, methods, study design, analytics, standards of rigor, and application to problems.This session focuses on these emerging fields, examining D&I sciences across the entire translational science spectrum. It explores state of D&I sciences, benefits of D&I in every stage of translation, and expansion of D&I capacity through workforce development. Led by members from the NCATS Dissemination &Implementation (D&I) Research Working Group, the session encourages participants to increase impact of their research using D&I approaches that build bridges, span barriers, and link evidence to practice and impact. Rapid fire topics offer an overview, drill down on each stage of translational science, address scientific workforce capacity and team science, and envision the future of D&I applied to translational research. Discussions operationalize concepts through examples, including COVID-19, journal articles, and resources for further depth.
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Meaningful Community Engagement within a Context of Physical Distance, Misinformation and Scientific Uncertainty
Description: This Mini Symposium will explore how community engagement scholars have adapted strategies to sustain partnerships and respond to COVID-19. The symposium will explore bidirectional communication, issues of power and inequity, social capital and trust, context and change within an evolving response to the COVID-19 pandemic.
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Nothing About Us Without Us: Lessons Learned from a Community-Engaged Translational Study in Access to Vision Care
Description: In this session, Team Cooke Bailey (TCB) members and collaborators will highlight the importance of team science and community-engaged research for health and genetic studies by discussing successes, barriers, challenges, and lessons learned from the All Eyes On Us: Understanding Vision Disparities in Cleveland, Ohio study, designed to incorporate community, diversity, and lived experience to understand participants perceptions of and barriers to vision care.
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Opportunities for Translating Workforce Development Strategies Across the Consortia Before, During, and After a Pandemic
Description: This panel session will provide an overview and discussion of the effort to determine the portability of an existing workforce development program for clinical research staff established at Mayo Clinic, and its implementation at Penn State University and University of Mississippi Medical Center as part an effort funded through a CTSA supplement grant. Panel members will discuss the principles of a robust clinical research workforce development program, key considerations for implementation at the partnering institutions, audiences served, and the portability of the program infrastructure to additional CTSA hubs. In addition, the panel will highlight the collaborative effort to pivot workforce development activities to virtual platforms in response to the COVID-19 pandemic. Participants will engage in discussion of applications of these experiences in their own settings.
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Prepped for Success: Initiating Collaborations with Statisticians Pre- and Post- COVID
Description: For new investigators, initiating a collaboration with a statistician may seem a bit uncomfortable, even scary, due to not knowing what to expect. Post-COVID, it may be even harder to know what to expect. However, the COVID pandemic has forced us to make adaptations that, in some ways, have made collaborations with statisticians easier, with the ability to access expertise not only locally but also nationally (and even globally). Regardless of whether the meeting takes place in-person or remotely, a successful and productive collaboration can be built upon a successful first meeting, which includes discussing and clearly defining both the goals of the study and how the statistician and the investigator will work together to achieve those goals. This panel discussion will provide tips for a successful first meeting and for further collaboration, as well as set forth the roles and responsibilities for both the researcher and the statistician.
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Progress, Challenges and Opportunities Toward Implementation of AI and Data Science in Medicine
Description: Electronic Health Record (EHR) systems are sophisticated enough now to capture all aspects of clinical patient care and continue to improve. Over the time they have been in place, healthcare delivery systems have accumulated significant and increasingly useful data about patient encounters, business processes and financial operations. Data are now standardized using increasingly sophisticated and interoperable terminologies and information models (such as FHIR), enabling method development with ease. These data and methods show great promise for enabling the Learning Health System through predictive and prescriptive analytics guided by artificial intelligence to improve healthcare. In this panel discussion, we will focus on the issues spanning the delivery science of machine learning into the clinical workflow. We will discuss our experiences and highlight foci of interest to the clinical and translational research community. Panelists will present short talks and then participate in audience discussion. We will describe investments in operational data science and what our expected outcomes are.
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Scaling Up Efforts to Establish and Support Numerous Community-Academic Research Teams Concurrently for both Investigator-Initiated and Community-Driven Research
Description: Community engagement is increasingly recognized as a critical element of translational research to ensure the quality and relevance of clinical and translational studies, improve implementation of health discoveries, and improve health outcomes. However, successful engagement requires establishing relationships with community partners, training for both investigators and community partners to support effective collaboration, and engagement of multiple stakeholders. This type of community engagement is time consuming, and requires significant investigator expertise and research readiness from communities. This session will describe a community-academic connections program (henceforth Connections Program) at the Institute of Translational Health Sciences, which enables investigators to quickly engage multiple community stakeholders and embeds training, technical support and evaluation throughout the project lifespan. The Connections Program can be scaled up to support numerous research studies without overburdening the CTSA-based coordinating center or community engagement program.
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The Intersection of Precision Medicine and Health Equity in Combating COVID-19
Description: The spread of COVID-19 throughout the United States has brought existing health disparities into new focus as the various health, economic, and social harms of COVID-19 disproportionately fall upon minority communities. This workshop will explore the intersection of precision medicine and health equity in addressing COVID-19 in minority communities. Interdisciplinary experts will discuss efforts by the NIMHD Transdisciplinary Collaborative Centers for Health Disparities Research Focused on Precision Medicine (TCC-PM) to address the adverse effects of COVID-19.
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Three Steps to Save Time and Increase Engagement of Communities, Stakeholders and Policy Makers
Description: Capturing and retaining attention has never been more challenging. At the same time, the stakes of clearly communicating the impact of new research to communities has also never been greater. Clear, concise and compelling communication is fundamentally vital to the translation of research to patient impact. Composing a compelling narrative, designing effective slides, and perfecting a compelling delivery takes time and effort. Learning how to maximize these investments allows more time for pursuing vital research. How to turn complex science into clear and concise narratives. How to leverage the genuine authenticity of your personality and voice.
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Tools to Build Communication Skills in Predoctoral Training Programs
Description: A key factor for success in science is the ability to communicate clearly and succinctly utilizing language appropriate to the audience. NIH has defined communication competency as the ability to communicate clinical and translational research findings to different groups of individuals, including colleagues, students, the lay public and the media. This workshop will focus on oral presentation skills and through brief presentations and utilization of tools will provide critical information to: 1) Understand the professional VALUE of oral presentations 2) Identify WHO your audience is 3) Identify WHAT is the relevant information that they need to hear 4) Identify WHY this audience need to know this 5) Give an effective presentation 6) Critique presentations and provide constructive feedback. An Oral Presentation Evaluation Tool will be provided to each trainee to use throughout the ACTS meeting and begin building their critiquing skills.
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Training, Acquisition of Know-How & Mentorship in Clinical and Translational Research for Faculty Members/Clinicians in the Health Professions, during the COVID-19 Pandemia and Other Natural Disasters
Description: Join a panel that will introduce a supportive model to train Health Professionals /clinicians and others in Clinical and Translational Research (CTR), providing evidence of activities that work. Training in CTR for early and mid-career faculty and tenured faculty in decision making positions advances the support for CTR and provides new alternatives to develop their academic careers. Four former trainees will present their specific development benchmarks. The session will highlight the agility of the model to evolve and to attend to trainees’ needs during 2020, a year in which there were earthquakes and challenges posed by the COVID19 pandemic.
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Translational Science 2020
What: Translational Science 2020 - Virtual Sessions 1
When: April 15, 2020
- Welcome | Fred Meyers, MD, MACP
- Introduction of CR Forum Top 10 | Anne B. Curtis, MD MACP, FACC, FHRS, FAHA
- Canagliflozin and Renal Outcomes in Type 2 Diabetes and Nephropathy, Kenneth Mahaffey, MD
- Hematopoietic Stem Cell Transplantation for Frequently Relapsing Multiple Sclerosis, Richard Burt, MD
- Skin-like Devices for Wireless Monitoring of Vital Signs in Neonatal Intensive Care, John Rogers, MD
- CR Forum Q&A | Moderated by Harry Selker, MD
- Panel Discussion: COVID-19: How Researchers Can Turn Crisis into Opportunity | Moderator: Robert Kimberly, MD
- Panelists: Simeon Abiola, PhD; Mark Burge, MD; Rajpreet Chahal, PhD; Martha Gay, PhD; Chris Lindsell, PhD; Fred Meyers, MD, MACP; Zachary Rivers, PharmD; Kathryn Sandberg, PhD; Liane Schneller, PhD, MS; Cherry Wongtrakool, MD
- Closing | Fred Meyers, MD, MACP
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What: Translational Science 2020 - Virtual Sessions 2
When: April 16, 2020
- Welcome | Chris Lindsell, PhD
- Fireside Chat with Amy Abernethy, MD, PhD | Interview by Scott Steele, PhD
- ACTS Abstract Presentations
- Unique Vaginal Microbiome Populations and Microbial Gene Content Among Women Who Naturally Control HIV Progression, Katherine Michel
- Nilotinib Alters MicroRNAs that Regulate Specific Autophagy and Ubiquitination Genes in the Cerebrospinal Fluid of Parkinson's Patients, Alan Fowler
- Deep-primed IL-15 Superagonist Improves Antiviral Efficacy of HIV-specific CD8+ T-Cells in Humanized Mouse Model, Chase McCann
- Moderated Q&A | Moderated by Kathryn Sandberg, PhD
- Translational Science’s Finest Hour – Use the Moment Well, David Skorton, MD
- ACTS Abstract Presentations | Moderated by Kathryn Sandberg, PhD
- Hollow, Degradable poly(N-Isopropylacrylamide) Derived Nanoparticles for the Delivery of Anti-Inflammatory Peptides for the Treatment and Prevention of Post-Traumatic Osteoarthritis, Marcus Deloney
- Matrix-bound Nanovesicles as a Novel Therapeutic Option for the Treatment of Rheumatoid Arhtritis, Raphael Crum
- Heart Transplant Candidates Listed at Low First-Offer Organ Acceptance Rate Centers are More Likely to Die Waiting, Ashley Choi
- Closing | Chris Lindsell, PhD
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Translational Science 2019
Education and Career Development Bundle
This bundle includes the following sessions, recorded at Translational Science 2019:
- Novel Approaches to Successful Grant Writing (Transitions)
- Mentorship is Vital for Success During Mid-Career
- Scientific Communication Skills for Pre-Doctoral Trainees
- How to Write a Successful F Award
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Data in Science Bundle
This bundle includes the following sessions, recorded at Translational Science 2019:
- Conducting Full-Spectrum Translational Research: Big Data Meets Embedded Mechanistic Studies
- Predictive Modeling and AI in Healthcare: What to Do with Garbage
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Novel Approaches to Successful Grant Writing (Transitions)
Recording: Introduces a novel way for teaching and learning the skill of writing NIH-style research proposals, as well as key elements of transitioning from K to R funding.
Speaker: Richard McGee, Jr, PhD, Northwestern University
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Mentorship is Vital for Success During Mid-Career
Recording: Early & Mid-career faculty, post-tenure faculty, and faculty in leadership positions can all benefit from a mentoring relationship. Mentoring can shape the plan for the mid-career transition and mid career related priorities. A supportive & collaborative network for faculty at mid-career is just as important, if not more so, than in early career faculty development. Mid-Career faculty & Scientists are often left to consider various questions of meaning/identity of career, navigating a plateau when professional goals are less clear, leadership opportunities within the organization and nationally, and legacy of career.
Speakers: Frederick J. Meyers, MACP, University of California, Davis and Sharon Rounds, MD, Brown University
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Scientific Communication Skills for Pre-Doctoral Trainees
Recording: A key factor for success in science is the ability to communicate clearly and succinctly utilizing language appropriate to the audience. NIH has defined communication competency as the ability to “communicate clinical and translational research findings to different groups of individuals, including colleagues, students, the lay public and the media.” A scientist’s career will “soar” or “sink” based on their ability to communicate their science through oral and written communication channels. This workshop, recorded at Translational Science 2019, focuses on oral presentation skills and through brief presentations and utilization of tools provides critical information to:
- Understand the professional VALUE of oral presentations
- Identify WHO your audience is
- Identify WHAT is the relevant information that they need to hear
- Identify WHY this audience need to know this
- Give an effective presentation
Speakers: Stephen C. Ekker, Mayo Clinic; Becca Gas, Mayo Clinic; Anthony Windebank, Mayo Clinic
Moderator: Karen Weavers, Mayo Clinic
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How to Write a Successful F Award
Recording: Covers how to put together a successful application for a NIH F-award to support their pre-doctoral research as a PhD or MD-PhD student or as a postdoctoral fellow.
Speakers: Linda M. McManus, University of Texas Health Sciences Center, San Antonio and Stephen C. Ekker, Mayo Clinic
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Conducting Full-Spectrum Translational Research: Big Data Meets Embedded Mechanistic Studies
Recording: The Rockefeller University Center for Clinical and Translational Science (RU-CCTS) Clinical Scholars (KL2) Program provides an optimal environment for translational investigator trainees to develop team science and leadership skills. Clinical scholars and early-career physician–scientists are encouraged to include T3–T4 translational aims to align with their T0-T1 experiments, by designing and performing a human subjects protocol under the supervision of a senior investigator mentor and a team of content expert educators.
This case presentation illustrates how an early-career physician-scientist posing basic science questions about metabolic outcomes of bariatric surgery engaged with a practice-based research network (PBRN) and clinicians at a Federally Qualified Health Center (FQHC), to jointly generate a set of exploratory hypotheses of interest to both basic scientists and practicing clinicians, and to examine these hypotheses in a de-identified electronic health records (EHR) data study (n=236) funded by a CTSA pilot grant. This initial single-site study was subsequently extended as part of a national “Big Data” study (n=65,093) conducted with PCORnet, a federated network of clinical data research networks (CDRNs). The national project secured external funding (PCORI), engaged community partners as co-investigators and coauthors, and disseminated results through presentations and publications (Annals of Internal Medicine 2018).
Goals of this “full-spectrum” translational research are to: (1) identify which patients will respond to bariatric surgery with significant and sustained weight loss and improvement in glucose homeostasis, and (2) generate mechanistic hypothesis to be tested on the bench with mouse models, and in a research hospital with noninvasive human protocols (imaging studies, biological specimens) to elucidate how bariatric surgery leads to weight loss and improvement in glucose homeostasis. Combining a CTSA and PBRN to train and engage basic scientists with community-based clincians and patients creates scientifically meaningful community–academic partnerships that accelerate translational science to implement discoveries and improve human health.
Speakers: Ana Beatriz Emiliano, MD, Berrie Diabetes Center, Columbia University Medical Center; Rabih Nemr, MD, FACS, Columbia University Medical Center; NYU Langone Brooklyn; Rhonda G. Kost, MD, Rockefeller University; Jonathan N. Tobin, PhD, Rockefeller University
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Trends in Genomic Analysis: Science, Technology, Translation and Policy
Recording: Examines current and emerging genomic sequencing and other genomic analysis approaches and programs, exploring the scientific, regulatory, and policy opportunities and gaps to be addressed in this area of precision medicine.
Speakers: Teri Manolio, MD, PhD, National Institue for Human Genome Research, NIH; Greg Feero, MD, PhD, Geisel School of Medicine at Dartmouth; Matthew R. Nelson, GSK; John W. Belmonth, MD, PhD, Clinical Genomics Group, Illumina Inc.; Zivana Tezak, PhD, Center for Devices and Radiological Heath, FDA
Moderator: Scott Steele, PhD, University of Rochester Medical Center
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Predictive Modeling and AI in Healthcare: What to Do with Garbage
Recording: Data from the electronic health record (EHR) are frequently used to generate predictive models, or as the basis of artificial intelligence tools, to support medical decision making and health care operations. There are fundamental limitations based on the quality of the underlying data. Missingness and errors are unlikely to be random, and shouldn’t be ignored. This is true both for developing the models and then for using these tools to make decisions at the individual patient level. In this session, recorded at Translational Science 2019, the presenter covers the principal challenges, how errors propagate through modeling processes, and how they translate to sub-optimal decision making. Potential solutions and opportunities for research are discussed.
Speaker: Jareen Meinzen-Derr, Cincinnati Children’s Hospital Medical Center
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Webinars
Webinar: Mount Sinai Health Hackathon: A Model of Experiential Team Science
When: November 21, 2019
Presenter: Janice Gabrilove, MD, FASP and Layla Fattah, MPharm, MEd
Launched in 2016 and now in it’s fourth year, the Mount Sinai Health Hackathon offers an innovative and novel model for team science education and entrepreneurship. Borrowing this format from the technology world, the Health Hackathon brings together individuals to form interdisciplinary teams with the aim of creating an innovative technology to solve a current problem in medical science or healthcare. This forum taps into the notion of “citizen science” and integrates diverse capabilities and domain expertise of front-line clinical providers, with insight into clinical phenotypes and care delivery challenges, with individuals reflective of wide-range of disciplines including basic science, engineering, programming, product design and business.
From an organizers perspective, the Health Hackathon aims to bring participants together in transdisciplinary teams around a shared problem, fostering experiential learning through communication, collaboration and problem-solving. It aims to cultivate an environment for participants to develop the skills and knowledge for creating technology that addresses the needs and unique challenges of the healthcare environment, and to promote healthcare innovation and an entrepreneurial ecosystem at Mount Sinai and beyond. In this webinar session, we aim to provide you with an overview of the Mount Sinai Health Hackathon experience by showcasing the vision, mission, outcomes and impact of this novel initiative. We will describe the planning involved to create a highly successful Health Hackathon, the content and format of the event, as well as outcome measures and evaluation tools we have utilized to measure the impact on team science. Our goal is to provide a new way to think about fostering team science, provide you with Health Hackathon best practices to consider, and inspire you to develop similar models of fostering team science education while promoting entrepreneurship.
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Webinar: Current Trends in Qualitative Methodology for Translational Science Research and Evaluation
When: July 8, 2020
Presenter: Clara Pelfrey, PhD and Joseph Kotarba, PhD
The purpose of this panel is to demonstrate the application of current qualitative methods to evaluate clinical and translational science programs, organizations, and enterprises. Time will be distributed evenly to the five presenters, who will speak for 8 minutes and allow for 4-5 minutes of Q & A. Learn more about the five presenters and their topics below.
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